What Blood Types Are More Resistant To HIV
According to medical evidence, there are people who are at a greater risk of HIV infection than others. This can be attributed to genetic mutation that brings about the HIV resistance factor.
The first genetic mutation associated with HIV susceptibility was identified in the mid-1990s. Known as the CCR5-Delta32mutation, it seems to confer strong resistance to infection by HIV. This gene mutation is found most commonly in certain European populations. That is possible because it was also associated with resistance to other diseases such as smallpox or the Bubonic Plague.”
What this simply means is that there are some people who might have been exposed to the HIV virus and never got infected. It is not a chance to take when it comes to protecting yourself from the virus but it is a fact that should be known.
In early 2009, a paper was published announcing that another genetic mutation may also confer some level of resistance to HIV. This mutation affects the level of expression of a protein known as Pk. Pk is found on the surface of several types of blood cells. In particular, it’s found on a wide range of cells that are susceptible to HIV infection. This small study found that cells with high levels of Pk were significantly harder to infect with HIV than cells with no Pk. The same scientists have also published a study showing that individuals with a condition (Fabry’s disease) that increases their levels of Pk seem to be resistant to one type of HIV.”
This genetic mutation has been a significant aspect in the functional cures seen with the London and Berlin patients. The bone marrow transplant contained the mutation and this led to he HIV resistance and functional cure.
Interestingly, this genetic resistance has played an important role in functional cure research. The case of the Berlin patient involved a man who was given bone marrow cells from someone with the CCR5 mutation.”
When this mutation is combined with antiretroviral treatment, it seemed to get rid of the HIV virus completely. According to the patients’ doctors, the virus seemed to have been eliminated from the viral reservoir. In the midst of this information it is important to keep the following facts in mind:
The study has been heavily publicized as saying that your blood type can protect you against HIV. Pk is a way of typing blood. However, it is not commonly used and not part of either the A/B/O or Rh typing systems. Furthermore, the study in question only looked at in vitro susceptibility and their earlier study in people only found resistance to one type of HIV. Therefore it is important not to overstate the results of the study. It seems likely that people with mutations that increase the amount of Pk will be more resistant to HIV than people with lower levels of Pk. This information may potentially lead to new types of HIV therapeutics. However, to say that blood type can protect against HIV infection is grossly premature.”
Living with the HIV virus can be a daunting experience. However, it is important that people living with HIV find a place where they can get support and also find love. The best way to do this is to join a HIV dating site where there are HIV singles looking for someone like you.
Source: This content first appeared on Which blood type is more resistant to HIV?